« Back
Home /
Anti-Human IL-17B - 25 µg

Anti-Human IL-17B - 25 µg

Item no.	LEIN-I-408-25ug
Manufacturer	Leinco Technologies
Amount	25 ug
Quantity options	100 ug 25 ug
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	1. Li, H.et al. (2000) PNAS. 97:773 2. Shi, Yet al. (2000) Journal of Biol. Chem. 275:19167
NCBI	27190
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Quality Tested by Leinco Western Blotting: To detect Human IL-17B this polyclonal antibody can be used at a concentration of 0.1-0.2 µg/ml. This polyclonal antibody should be used in conjunction with compatible second-step reagents such as PN:G505 and a chromogenic substrate such as PN:T343. The detection limit for Human IL-17B is 2 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. A suitable Western blotting control is PN:I-237.
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	IL-17B
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	IL17B is a disulfide-linked homodimer, also known as Cytokine CX1, NIRF [neuronal interleukin-17-related factor; neuronal IL17-related factor], Zcyto7, and IL20. IL17B is expressed by T-cells and stimulates the release of TNF-alpha and IL1-beta in the monocytic cell line, THP-1. It does not induce expression of IL1-alpha, IL6, IFN-gamma, or G-CSF in these cells.1, 2 IL-17B is known to stimulate the proliferation of chondrocytes, bone, and is highly expressed in nervous tissue, resulting in repair of diseased tissue. IL-17B, either alone or in combination with other cytokines or growth factors is known to aid wound healing.
Background	IL17B is a disulfide-linked homodimer, also known as Cytokine CX1, NIRF [neuronal interleukin-17-related factor; neuronal IL17-related factor], Zcyto7, and IL20. IL17B is expressed by T-cells and stimulates the release of TNF-alpha and IL1-beta in the monocytic cell line, THP-1. It does not induce expression of IL1-alpha, IL6, IFN-gamma, or G-CSF in these cells.^{1, 2} IL-17B is known to stimulate the proliferation of chondrocytes, bone, and is highly expressed in nervous tissue, resulting in repair of diseased tissue. IL-17B, either alone or in combination with other cytokines or growth factors is known to aid wound healing.
PubMed	IL-17B
Manufacturer - Specificity	Rabbit Anti-Human Interleukin-17B (IL-17B) recognizes Human IL-17B. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2830670
Formulation	This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level	< 0.01 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Human IL-17B (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Interleukin-17B, CX1, NIRF [Neuronal Interleukin-17-Related Factor, Neuronal IL17-Related Factor], Zcyto7, IL20, Cytokine-Like Protein ZCYTO7, Interleukin-17 Beta, IL-17B, MGC138900, MGC138901, IL-17B, Human IL-17B, Anti-Human IL-17B, Cytokine Zcyto7, cytokine-like protein ZCYTO7, IL17B, IL-17B, IL-17Binterleukin-17 beta, IL20, IL-20interleukin-17B, interleukin 17B, interleukin 20, Interleukin-20, MGC138900, MGC138901, neuronal interleukin-17 related factor, Neuronal interleukin-17-related factor, NIRF, ZCYTO7interleukin-20

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

LEIN-I-408-25ug-safety-datasheet.pdf