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Anti-Human IL-17R - 25 µg

Anti-Human IL-17R - 25 µg

Item no.	LEIN-I-627-25ug
Manufacturer	Leinco Technologies
Amount	25 ug
Quantity options	100 ug 25 ug 500 ug
Category	Antibodies Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, FC
Clone	133617
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Facchini, A. et al. (2007) J clin. Research clin. oncol. 133: 1017 2. Armitage, RJ. et al.(1997) Cytokine. 9(11):794-800.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	CyTOF®, FC, N, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	IL-17R
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Interleukin-17 receptor (IL-17R) Type 1 transmembrane glycoprotein which binds interleukin 17. IL-17R signaling is critical for pulmonary neutrophil recruitment and host defense against Gram-negative bacteria.1 It represents a marker for the metastasizing ability of osteosarcoma.1
Background	Interleukin-17 receptor (IL-17R) Type 1 transmembrane glycoprotein which binds interleukin 17. IL-17R signaling is critical for pulmonary neutrophil recruitment and host defense against Gram-negative bacteria.¹ It represents a marker for the metastasizing ability of osteosarcoma.¹
Other Applications Reported In Literature	Neutralization: At 2 μg/mL, this antibody will neutralize 70 - 90% of human IL-17 receptor-mediatedbioactivity in the presence of 25 ng/mL of rhIL-17 using IL-17-dependent secretion of IL-6by the NHDF cell line as an assay. CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
PubMed	IL-17R
Manufacturer - Specificity	Mouse Anti-Human Interleukin 17 Receptor (IL-17R) (Clone 133617) recognizes an epitope on Human IL-17R. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2830749
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen	Purified Recombinant Human IL-17R (Accession # Q96F46)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Interleukin-17 Receptor, IL17R, CDw217, IL-17RA, IL17RA, MGC10262, 133617, IL-17R, Human, Anti-Human IL-17R, CD217 antigen, CD217, Cdw217, CDw217interleukin 17 receptor, hIL-17R, IL-17 R, IL-17 RA, IL-17 receptor A, IL17RA, IL-17RA, IL-17RAMGC10262, IL17Rinterleukin-17 receptor A, interleukin 17 receptor A

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-I-627-25ug-safety-datasheet.pdf