Comparison

Anti-Human IL-10 Rβ (Clone 90220) - 100 µg

Item no. LEIN-I-715-100ug
Manufacturer Leinco Technologies
Amount 100 ug
Quantity options 100 ug 25 ug 500 ug
Category
Type Antibody Monoclonal
Applications WB, FC
Clone 90220
Specific against Human (Homo sapiens)
Host Mouse
NCBI 3588
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Shipping Condition Room temperature
Available
Manufacturer - Applications
CyTOF®, FC, N, WB
Manufacturer - Category
Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets
IL-10 Rβ
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description
Interleukin 10 receptor, beta subunit (IL10RB) is a subunit for the interleukin-10 receptor which has recently been designated CDW210B (cluster of differentiation W210B). The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction.
Background
Interleukin 10 receptor, beta subunit (IL10RB) is a subunit for the interleukin-10 receptor which has recently been designated CDW210B (cluster of differentiation W210B). The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction.
Other Applications Reported In Literature
Neutralization: This antibody is useful for neutralization of Human IL-10 Rβ bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Human IL-10 Rβ (at 0.25 ng/ml) is 0.5 - 2 µg/ml.
CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
PubMed
IL-10 Rβ
Manufacturer - Specificity
Mouse Anti-Human Interleukin 10 Receptor Beta (IL-10 Rβ) (Clone 90220) recognizes an epitope on Human IL-10 Rβ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2830836
Formulation
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level
< 0.1 EU/µg as determined by the LAL method
Immunogen
NS0-Derived Recombinant Human Interleukin-10 Receptor β Extracellular Domain (Accession # Q08334)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Interleukin-10 Receptor Beta, IL10RB, CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, 90220, IL-10 Rβ, Human, Anti-Human IL-10 Rβ, CDw210b antigen, CDw210b, CRF2-4IL-10R subunit 2, CRFB4, CRFB4human transmembrane receptor protein, cytokine receptor10CDW210B, D21S58, D21S66, IBD25, IL-10 R beta, IL-10 receptor subunit beta, IL10R beta, IL-10R2, IL-10R2IL-10R subunit beta, IL10RB, IL-10Rb, interleukin 10 receptor, beta, Interleukin-10 receptor subunit 2, interleukin-10 receptor subunit beta, member 4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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