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Anti-Human CD119 (IFN-γ Rα Chain) - DyLight® 550 - 100 µg

Anti-Human CD119 (IFN-γ Rα Chain) - DyLight® 550 - 100 µg

Item no.	LEIN-I-970-100ug
Manufacturer	Leinco Technologies
Amount	100 ug
Quantity options	100 ug 200 ug 50 ug
Category	Antibodies Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	GIR-208
Specific against	Human (Homo sapiens)
Host	Mouse
NCBI	3459
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	Quality Tested by Leinco FC The suggested concentration for clone GIR-208 conjugated antibody for staining cells in flow cytometry is ≤ .25 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	IFNγ Rα
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Background	IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
PubMed	IFNγ Rα
Excitation Laser	Yellow Laser (563 nm)
Manufacturer - Research Area	Immunology
Manufacturer - Specificity	Clone GIR-208 recognizes an epitope on human IFNγ Rα.
RRID	AB_2831046
Concentration	0.2 mg/ml
Formulation	This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Immunogen	Purified Recombinant Human IFNGR1 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, IFNγ Rα, Interferon Gamma R Alpha Chain, CD119, GIR 208, IFNGR1, Human, Anti-Human IFN-γ Rα Chain - DyLight® 550

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-I-970-100ug-safety-datasheet.pdf