Comparison

Anti-Human CCL22 (Clone 57226) - 25 µg

Item no. LEIN-M1092-25ug
Manufacturer Leinco Technologies
Amount 25 ug
Quantity options 100 ug 25 ug 500 ug
Category
Type Antibody Monoclonal
Applications WB, ELISA
Clone 57226
Specific against Human (Homo sapiens)
Host Mouse
Citations 1. Sozzani, S. et al. (2001) Eur. J. Immunol. 31:812
2. Elias, CG. et al. (1998) J Immunol. 161:5027
3. Gray, PW. et al. (1997) J Exp Med. 185:1604
4. Teixeira, MM. et al. (2003) J Leuko Biol. 73:356
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Shipping Condition Room temperature
Available
Manufacturer - Applications
ELISA Cap, N, WB
Manufacturer - Category
Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets
CCL22
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This lyophilized monoclonal antibody should be stored desiccated at -20°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description
Chemokine (C-C motif) ligand 22, also known as CCL22 is secreted by dendritic cells and macrophages, and elicits its effects on its target cells by interacting with cell surface chemokine receptors such as CCR4.1 CCL22 selectively chemo-attract Th2 cytokine-producing cells2, 3 and acts as an important activator of eosinophils once these cells have migrated into tissue.4
Background
Chemokine (C-C motif) ligand 22, also known as CCL22 is secreted by dendritic cells and macrophages, and elicits its effects on its target cells by interacting with cell surface chemokine receptors such as CCR4.1 CCL22 selectively chemo-attract Th2 cytokine-producing cells2, 3 and acts as an important activator of eosinophils once these cells have migrated into tissue.4
Other Applications Reported In Literature
Neutralization: This antibody is useful for neutralization of Human MDC bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Human MDC (at 10 ng/ml) is 0.6 - 3 µg/ml.
PubMed
CCL22
Manufacturer - Research Area
Chemokine
Manufacturer - Specificity
Mouse Anti-Human Chemokine (C-C Motif) Ligand 22 (CCL22) (Clone 57226) recognizes an epitope on Human CCL22. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2831224
Formulation
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level
< 0.1 EU/µg as determined by the LAL method
Immunogen
Purified Recombinant Human CCL22 (Accession # O00626.1)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Chemokine (C-C Motif) Ligand 22, MDC, A-152E5.1, ABCD-1, DC/B-CK, MGC34554, SCYA22, STCP-1, 57226, CCL22, Human, Anti-Human CCL22, A-152E5.1, ABCD-1, CC chemokine STCP-1, C-C motif chemokine 22, CCL22, chemokine (C-C motif) ligand 22, DC/B-CK, Macrophage-derived chemokine, MDC, MDCStimulated T-cell chemotactic protein 1, MGC34554, SCYA22MDC(1-69), small inducible cytokine A22, small inducible cytokine subfamily A (Cys-Cys), member 22, Small-inducible cytokine A22, STCP-1, stimulated T cell chemotactic protein 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 ug
Available: In stock
available

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