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Anti-Human CXCL9 (Clone 49106) - 500 µg

Anti-Human CXCL9 (Clone 49106) - 500 µg

Item no.	LEIN-M1103-500ug
Manufacturer	Leinco Technologies
Amount	500 ug
Quantity options	100 ug 25 ug 500 ug
Category	Antibodies Flow Cytometry Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Monoclonal
Applications	WB, FC, ICC, ELISA
Clone	49106
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Farber, JM. et al. (2002) J. Immunol. 169: 1433
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	CyTOF®, ELISA Cap, FC, ICC, N, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	CXCL9
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-γ. Mig may be important not only to recruit T cells to peripheral inflammatory sites, but also in some cases to maximize interactions among activated T cells, B cells, and dendritic cells within lymphoid organs to provide optimal humoral responses to pathogens.1
Background	Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-γ. Mig may be important not only to recruit T cells to peripheral inflammatory sites, but also in some cases to maximize interactions among activated T cells, B cells, and dendritic cells within lymphoid organs to provide optimal humoral responses to pathogens.¹
Other Applications Reported In Literature	Neutralization: This antibody is useful for neutralization of Human MIG bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human MIG (at 1 ng/ml) is 15 - 30 µg/ml. CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation. Immunocytochemistry: Suitable for use at concentration of 8-25 µg/mL.
PubMed	CXCL9
Manufacturer - Research Area	Chemokine
Manufacturer - Specificity	Mouse Anti-Human Monokine Induced by Interferon-Gamma (MIG) (Clone 49106) recognizes an epitope on Human MIG. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2831229
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Human CXCL9 (Accession # Q07325)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Chemokine (C-X-C Motif) Ligand 9, CMK, Humig, MIG, SCYB9, Crg-10, 49106, CXCL9, Human CXCL9, Anti-Human CXCL9, chemokine (C-X-C motif) ligand 9, CMK, crg-10, C-X-C motif chemokine 9, CXCL9, Gamma-interferon-induced monokine, Humig, MIG, MIGSmall-inducible cytokine B9, monokine induced by gamma interferon, SCYB9Monokine induced by interferon-gamma

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-M1103-500ug-safety-datasheet.pdf