Comparison

Anti-Human PARC (CCL18) - 25 µg

Item no. LEIN-M172-25ug
Manufacturer Leinco Technologies
Amount 25 ug
Quantity options 100 ug 25 ug
Category
Type Antibody Primary
Applications WB, FC
Specific against Human (Homo sapiens)
Host Caprine
Citations 1. Nomiyama, H. et al. (1997) J. Biol. Chem. 272: 5846
2. Kucharzik, T. et al. (2005) J. Pathol. 166: 1647
NCBI 6362
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Shipping Condition Room temperature
Available
Manufacturer - Applications
CyTOF®, FC, WB
Manufacturer - Category
Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets
PARC
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description
Macrophage Inflammatory Protein-4 (MIP-4) produced in E.Coli is a single, non-glycosylated polypeptide that attracts lymphocytes but not monocytes or granulocytes and is involved in B cell migration into B cell follicles in lymph nodes. It attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T cells, CD4+ and CD8+ T cells and thus may play a role in both humoral and cell-mediated immunity responses. MIP-4 is expressed at high levels in lung, lymph nodes, placenta, and bone marrow, not expressed by peripheral blood monocytes, and a monocyte-to-macrophage differentiation is a prerequisite for expression.
Background
Macrophage Inflammatory Protein-4 (MIP-4) produced in E.Coli is a single, non-glycosylated polypeptide that attracts lymphocytes but not monocytes or granulocytes and is involved in B cell migration into B cell follicles in lymph nodes. It attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T cells, CD4+ and CD8+ T cells and thus may play a role in both humoral and cell-mediated immunity responses. MIP-4 is expressed at high levels in lung, lymph nodes, placenta, and bone marrow, not expressed by peripheral blood monocytes, and a monocyte-to-macrophage differentiation is a prerequisite for expression.
Other Applications Reported In Literature
CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
PubMed
PARC
Manufacturer - Research Area
Chemokine
Manufacturer - Specificity
Rabbit Anti-Human Macrophage Inflammatory Protein-4 (MIP-4) recognizes Human MIP-4. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID
AB_2831359
Formulation
This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level
< 0.1 EU/µg as determined by the LAL method
Immunogen
Purified Recombinant Human PARC (> 98%)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Polyclonal Antibody, PARC, Macrophage Inflammatory Protein-4, MIP-4, SCYA18, DC-CK1, AMAC-1, DCCK1, CKb7, CCL18, PARC, Human PARC CCL18, Anti-Human PARC CCL18, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, AMAC1CC chemokine ligand 18, AMAC-1Small-inducible cytokine A18m CCL18, chemokine C-C motif ligand 18 pulmonary and activation-regulated, CKb7, DC-CK1, DC-CK1CC chemokine PARC, DCCK1Macrophage inflammatory protein 4, Dendritic cell chemokine 1, MIP4, MIP-4, MIP-4C-C motif chemokine 18, PARC, PARCPulmonary and activation-regulated chemokine, SCYA18chemokine C-C, dendritic, small inducible cytokine A18, small inducible cytokine subfamily A Cys-Cys, member 18, pulmonary andactivation-regulated

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close