Anti-Human CCL23 - 25 µg

Item no.	LEIN-M181-25ug
Manufacturer	Leinco Technologies
Amount	25 ug
Quantity options	100 ug 25 ug
Category	Neuroscience Neuroinflammation Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	1. Huang, SA. et al. (2007) J Experimental Hematol. 15: 496 2. Woisetschläger, M. et al. (2007) J Immunol 178: 4335 3. Kim, J. et al. (2006) Biochemical and biophysical res communications 340:498
NCBI	6368
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	N, WB
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	CCL23
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody should be stored desiccated at -20°C. The reconstituted antibody can be stored for at least six weeks at 4°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family.1 It is primarily expressed in cells of the myeloid lineage.2 CCL23 induces endothelial cell migration and tube formation and enhances the expression of MMP-2 mRNA and protein levels in endothelial cells. CCL23 may play a direct role in angiogenesis.3
Background	Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family.¹ It is primarily expressed in cells of the myeloid lineage.² CCL23 induces endothelial cell migration and tube formation and enhances the expression of MMP-2 mRNA and protein levels in endothelial cells. CCL23 may play a direct role in angiogenesis.³
Other Applications Reported In Literature	Neutralization: This antibody is useful for neutralization of Human CCL23 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human CCL23 (at 20 ng/ml) is 0.5 - 2.5 µg/ml.
PubMed	CCL23
Manufacturer - Research Area	Chemokine
Manufacturer - Specificity	Rabbit Anti-Human Chemokine (C-C Motif) Ligand 23 (CCL23) recognizes Human CCL23. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2831365
Formulation	This antigen affinity purified polyclonal antibody is aseptically filtered and lyophilized from PBS with no carrier proteins or preservatives added.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Human CCL23 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Chemokine (C-C Motif) Ligand 23, SCYA23, Ckb-8, Myeloid Progenitor Inhibitory Factor-1 (MPIF-1), MIP-3, CKb8, HMRP-2A (Human MIP-Related Protein 2A), CCL23, Human CCL23, Anti-Human CCL23, CCL23/MPIF-1, MPIF1, MPIF-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-M181-25ug-safety-datasheet.pdf