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Anti-Mouse NK1.1 [Clone PK136] — Purified - 500 µg

Anti-Mouse NK1.1 [Clone PK136] — Purified - 500 µg

Item no.	LEIN-N106-500ug
Manufacturer	Leinco Technologies
Amount	500 ug
Quantity options	100 ug 500 ug
Category	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies
Type	Antibody Monoclonal
Applications	FC, IP, IHC
Clone	PK136
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Citations	Koo, G. C. and Peppard, J. R. (1986) Hybridoma 3:301
NCBI	17059
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	FC, IHC FF, IP
Manufacturer - Category	Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets	NK1.1
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. NK1.1 contains a transmembrane domain and a cytoplasmic domain that are characteristic of C-type lectins. The function of NK cells is to mediate cytotoxicity and to secrete cytokines after immune stimulation. NK1.1 has been correlated with lysis of tumor cells In vitro and rejection of bone marrow allografts In vivo. It is also involved in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 is commonly used as a mouse NK cell marker.
Background	NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. NK1.1 contains a transmembrane domain and a cytoplasmic domain that are characteristic of C-type lectins. The function of NK cells is to mediate cytotoxicity and to secrete cytokines after immune stimulation. NK1.1 has been correlated with lysis of tumor cells In vitro and rejection of bone marrow allografts In vivo. It is also involved in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 is commonly used as a mouse NK cell marker.
PubMed	NK1.1
Manufacturer - Research Area	Immunology, Innate Immunity
Manufacturer - Specificity	Clone PK136 recognizes mouse NK1.1.
RRID	AB_2831384
Concentration	0.5 mg/ml
Formulation	This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	NK-1.1 is encoded by the NKR-P1B/NKR-P1C gene and expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Natural Killer Cells, PK136, Anti-Mouse Natural Killer Cells Purified, NK1.1, CD161

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-N106-500ug-safety-datasheet.pdf