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Anti-Human NGF R - 0.1 mg

Anti-Human NGF R - 0.1 mg

Item no.	LEIN-N149-0.1mg
Manufacturer	Leinco Technologies
Amount	0.1 mg
Quantity options	0.1 mg 20 ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	1. Ashworth, A. et al. (2006) Modern Path. 19: 307 2. Carter, BD. et al. (2004) Prog. Brain Res. 146: 25 3. Itano, T. et al. (2001) Acta Med Okayama 55: 19
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	IHC FF, IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	NGF R
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation.1 It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination.2 p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism.3
Background	Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation.¹ It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination.² p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism.³
PubMed	NGF R
Manufacturer - Specificity	Rabbit Anti-Human Nerve Growth Factor Receptor (NGFR) recognizes Human NGFR. This polyclonal antibody was purified using affinity chromatography.
RRID	AB_2831409
Concentration	0.5 mg/ml
Formulation	This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, NGF R, CD271, TNFRSF16, P75 (Neurotrophin Receptor) NTR, LNGFR, NGF R, Human, Anti-Human NGF R, NGFR Antibody, CD271, p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, Tumor necrosis factor receptor superfamily member 16, NGF receptor

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-N149-0.1mg-safety-datasheet.pdf