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Anti-Bovine PKC-Biotin - 0.25 mg

Anti-Bovine PKC-Biotin - 0.25 mg

Item no.	LEIN-P108-0.25mg
Manufacturer	Leinco Technologies
Amount	0.25 mg
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IHC
Clone	MC5
Specific against	Cattle (Bovine)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	IHC FF, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	Protein Kinase C
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	Anti-PKC-Biotin (clone MC5) may be used to block both proteolysis and down-regulation of PKC activity. The antibody reacts with the intact molecule and may be used to localize PKC activity and to study the role of proteolysis in the activation of the Protein Kinase C pathway.
Background	Anti-PKC-Biotin (clone MC5) may be used to block both proteolysis and down-regulation of PKC activity. The antibody reacts with the intact molecule and may be used to localize PKC activity and to study the role of proteolysis in the activation of the Protein Kinase C pathway.
PubMed	Protein Kinase C
Manufacturer - Research Area	Apoptosis, Cell Biology, Immunology
Manufacturer - Specificity	Anti-Protein Kinase C (PKC) recognizes the intact (Mr 79-80 kDa) calcium-activated, phospholipid-dependent Protein Kinase C in bovine brain. The antibody strongly cross-reacts with PKC in human, mouse and rat cells.¹ Anti-PKC (clone MC5) binds to an epitope at the hinge region of the enzyme, the site of phorbol-ester-induced proteolysis which is thought to down-regulate PKC activity in intact cells.^{1, 2} Monoclonal MC5 reacts with PKC-α/ß₁/ß₂ isoforms.
RRID	AB_2831508
Concentration	0.5 mg/ml
Formulation	This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Protein Kinase C, MC5, PKC, Bovine, Anti-Bovine PKC Protein Kinase C-Biotin

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-P108-0.25mg-safety-datasheet.pdf