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Human TSH Beta

Human TSH Beta

Item no.	LEIN-T102-1.0mg
Manufacturer	Leinco Technologies
Amount	1 mg
Quantity options	1 mg 10 mg 11 mg 250 mg 500 mg 5 mg
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Clone	195
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. (1998) Bowen A 2. McPherson et al. (2000) Placenta 24: 941 3. Wenger, R H et al. (2003) Wildmann's Clinical Interpretation of Laboratory Tests
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Category	Primary Monoclonal Antibodies>Endocrinology Hormones
Manufacturer - Targets	Thyroid Stimulating Hormone Beta
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This Purified Antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3
Background	Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone¹ that regulates the endocrine function of the thyroid gland.² The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.³
Cross Reactivity	Paired with Leinco Prod. No. T100, Clone No. 154: TSH 100%, BhCG < 1%, ihCG < 1%, LH < 1%, FSH < 1%. Paired with Leinco Prod. No. T101, Clone No. 183: TSH 100%, BhCG < 1%, ihCG < 1%, LH 1%, FSH < 1%.
PubMed	Thyroid Stimulating Hormone Beta
Manufacturer - Research Area	Hormones, IVD Raw Material
Manufacturer - Specificity	Mouse Anti-Human Thyroid Stimulating Hormone Beta (TSH-β) (Clone 195) recognizes Human Thyroid Stimulating Hormone Beta. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2737562
Concentration	≥ 5.0 mg/ml
Formulation	This purified antibody is supplied in 0.05 M phosphate buffered saline (PBS), pH 7.4, containing 0.1% sodium azide.
Immunogen	Purified Recombinant Human TSH-β (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Thyroid Stimulating Hormone Beta, HCG, GPH, GPHA1, CGA, Thyrotropin, 195, TSH-β, Human, Anti-Human Thyroid Stimulating Hormone Beta Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-T102-1.0mg-safety-datasheet.pdf