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Anti-Mouse Vγ2 TCR - FITC - 50 µg

Anti-Mouse Vγ2 TCR - FITC - 50 µg

Item no.	LEIN-T212-50ug
Manufacturer	Leinco Technologies
Amount	50 ug
Quantity options	500 ug 50 ug
Category	Antibodies Flow Cytometry Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	UC3-10A6
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Quality Tested by Leinco Flow Cytometry: This antibody has been quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. Each lot of this antibody is quality control tested.
Manufacturer - Category	Mouse T-Cell Receptor Complex\|Primary Monoclonal Antibodies
Manufacturer - Targets	Vγ 2 T-Cell Receptor
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This FITC monoclonal antibody conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Background	The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Function	Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens.
PubMed	Vγ 2 T-Cell Receptor
Excitation Laser	Blue Laser (490 nm)
Manufacturer - Research Area	Adaptive Immunity, Immunology
Manufacturer - Specificity	This antibody reacts with Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes.
RRID	AB_2892975
Concentration	0.2 mg/ml
Formulation	This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Product Preparation	The antibody was purified by protein a affinity chromatography, and conjugated with FITC under optimal conditions.
Antigen Distribution	Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
Immunogen	G8 mouse T cells
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-T212-50ug-safety-datasheet.pdf