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Anti-Human TNF-Related Weak Inducer of Apoptosis (TWEAK) - 0.1 mg

Anti-Human TNF-Related Weak Inducer of Apoptosis (TWEAK) - 0.1 mg

Item no.	LEIN-T309-0.1mg
Manufacturer	Leinco Technologies
Amount	0.1 mg
Quantity options	0.1 mg 20 ug
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	1. Burkly, LC. et al. (2005) Oncogene 24: 2613 2. Young, LS. et al. (2003) Biochem Biophys Res Commun. 305: 789 3. Kumar, A. et al. (2007) FASEB J. 21: 1857 4. Hsueh, A. et al. (2006) Molecular Endo. 20: 2528
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	TWEAK
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF ligand family1 that has pleiotropic biological functions including proapoptotic, proangiogenic and proinflammatory activities.2 TWEAK induces skeletal muscle atrophy.3 TWEAK functions both as a type II transmembrane protein and as a cleaved soluble protein. TWEAK transcripts are expressed in heart, brain, skeletal muscle, pancreas, immune system, ovary, and placenta.4
Background	TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF ligand family¹ that has pleiotropic biological functions including proapoptotic, proangiogenic and proinflammatory activities.² TWEAK induces skeletal muscle atrophy.³ TWEAK functions both as a type II transmembrane protein and as a cleaved soluble protein. TWEAK transcripts are expressed in heart, brain, skeletal muscle, pancreas, immune system, ovary, and placenta.⁴
PubMed	TWEAK
Manufacturer - Specificity	Rabbit Anti-Human TWEAK recognizes Human, Mouse and Rat TWEAK. This polyclonal antibody was purified using affinity chromatography.
RRID	AB_2831897
Concentration	0.5 mg/ml
Formulation	This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, TNF-Related Weak Inducer of Apoptosis, TNFSF12, DR3LG, Apo3-Ligand, TWEAK, Human, Anti-Human TWEAK, TWEAK Antibody, APO3L, DR3LG, TWEAK, APO3L, UNQ181/PRO207, Tumor necrosis factor ligand superfamily member 12, APO3 ligand

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-T309-0.1mg-safety-datasheet.pdf