Anti-Mouse TRAIL R2 - 100 µg

ELISA Indirect, FC, N, WB

TRAIL R2

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Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.3

Neutralization: This antibody is useful for neutralization of Mouse TRAIL R2 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Mouse TRAIL R2 (at 12 ng/ml) is 0.4 - 1.2 µg/ml.
CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Goat Anti-Mouse TNF-Related Apoptosis-Inducing Ligand Receptor 2 (TRAIL R2) recognizes Mouse TRAIL R2. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

NS0-Derived Recombinant Mouse TRAIL Receptor 2 Extracellular Domain

Polyclonal Antibody, TNF-Related Apoptosis-Inducing Ligand Receptor 2, TNFRSF10B, CD262, DR5, KILLER, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, TRAIL R2, Mouse TRAIL R2, Anti-Mouse TRAIL R2, CD262 antigen, CD262, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL R2, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9