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Dynactin 1 (N-terminus) monoclonal antibody

Dynactin 1 (N-terminus) monoclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Neural Signaling Antibodies Cell Biology Cytoskeleton Immunoprecipitation Western Blot Motor proteins Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human
Isotype	IgG2b
Applications	WB, IP
Amount	100ul
Host	Mouse
Item no.	MB0011-100
Targets	DCTN1
eClass 6.1	32160702
eClass 9.0	42030590
Available
Swiss-Prot	Q14203
Application all	WB: 1:1000 IP: 1:50ca.1:200
Background	Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.
Product	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Purification and Purity	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	This antibody detects endogenous levels of DCTN1 and does not cross-react with related proteins
WB	Western blot detection of DCTN1 in A2780, TF-1, HepG2, MCF7, A431&K562 cell lysate (1:1000 diluted) .
IP	Immunoprecipitation analysis of Hela cell lysates using DCTN1 antibody
BiowMW	Predicted band size:150KDa Observed band size:150KDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	150 kDa dynein-associated polypeptide DAP-150, Dynactin 1, DCTN1, P135, DP-150, DAP-150, DCTN 1
Immunogen	Synthetic peptide, corresponding to the N-terminal of Human Dynactin 1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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