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Calpain 1 monoclonal antibody

Calpain 1 monoclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Targets for Rodent Neurosciences Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Proliferation Primary Antibodies
Type	Antibody Primary
Specific against	Human, Rat
Applications	FC, IHC
Amount	100ul
Host	Mouse
Item no.	MB9106-100
Targets	CAPN;;CAPNS1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P07384(Human) P97571(Rat)
Application_all	IHC:1:50-1:200 FC:1:50-1:100
Background	Calpain 1, also designated u-calpain, is an intracellular calcium-dependent protease that cleaves cyto-skeletal and submembranous proteins. Calpains are nonlysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+-dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpain-1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.
Product	Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProG purified.
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Specificity	Calpain 1 monoclonal antibody detects endogenous levels of Calpain 1 protein.
BiowMW	82 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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