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CD11b monoclonal antibody

CD11b monoclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunohistochemistry Immunocytochemistry Primary Antibodies Oligodendrocyte Markers
Type	Antibody Primary
Specific against	Human
Applications	FC, IHC, ICC
Amount	100ul
Host	Mouse
Item no.	MB9125-100
Targets	C3 ;;CD35;;ITGA3;;ITGA4;;ITGAM
eClass 6.1	32160702
eClass 9.0	32160702
Available
Swiss-Prot	P11215(Human)
Application_all	ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background	Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development.
Product	Mouse IgG2b, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProG affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	CD11b monoclonal antibody detects endogenous levels of CD11b protein.
BiowMW	127 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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