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Human BMP-7 antibody

Human BMP-7 antibody

Item no.	NKM-ABM0615-50ul
Manufacturer	NKMAX
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Neuroscience Neural Signaling Antibodies Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC, ELISA
Clone	4E7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
Citations	Gregory KE., et al. (2005) J. Biol, Chem. 280, 27970-27980. Sampath Tk., et al. (1990) J. Biol. Chem. 265:13198-13205. Godin RE., et al. (1998) Development. 125:3473-3482. Groppe J., et al. (2002) Nature. 420:636-642.
NCBI	NP_001710
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BMP 7,Bone morphogenetic protein 7,Eptotermin alfa,OP-1,Osteogenic protein 1
Available
Manufacturer - Type	Antibodies
Manufacturer - Applications	ELISA, WB, ICC/IF
Manufacturer - Category	Monoclonal Antibody
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	BMP-7 (bone morphogenetic protein-7), also known as OP-1 (osteogenic protein-1), is a member of the transforming growth factorbeta (TGFbeta) superfamily. BMP-7 plays an essential role during ontogeny of the mammalian eye and kidney, also, is expressed in heart, lung, small intestine, limb bud and teeth. In addition, noggin, one of the soluble BMP antagonists, regulated the action of BMPs on mesenchymal precursor cells, partially through a feedback type of inhibition.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human BMP7 (293-431aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-G affinity chromatography
Gene Category	Hormones & Cytokines
Manufacturer - Search Terms	Osteogenic protein1, Osteogenic protein 1, OP-1, OP1, OP 1, Eptotermin alfa, Bone morphogenetic protein 7, BMP 7, BMP7, BMP-7, ABM0615-10ug, ABM0615-20ug, ABM0615-50ug, ABM0615-100ug, ABM0615-250ug, ABM0615-500ug, ABM0615-1mg, ABM0615-010, ABM0615-020, ABM0615-050, ABM0615-100, ABM0615-250, ABM0615-500, ABM0615-01M
Manufacturer - Similar Names	Osteogenic protein1, Osteogenic protein 1, OP-1, OP1, OP 1, Eptotermin alfa, Bone morphogenetic protein 7, BMP 7, BMP7, BMP-7, ABM0615-10ug, ABM0615-20ug, ABM0615-50ug, ABM0615-100ug, ABM0615-250ug, ABM0615-500ug, ABM0615-1mg, ABM0615-010, ABM0615-020, ABM0615-050, ABM0615-100, ABM0615-250, ABM0615-500, ABM0615-01M
IF Comment	ICC/IF analysis of BMP7 in HeLa cells. The cell was stained with ABM0615 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment	The extracts of mouse kidney (MK) and rat heart (RH) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human BMP7 antibody (1:1, 000). Protein was visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/4/2025

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