Human Apolipoprotein A1/APOA1 antibody

Monoclonal Antibody

Apolipoprotein A1 (APOA1) is the main protein component of high density lipoprotein (HDL) in plasma. This protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in APOA1 are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. High level of APOA1 is regarded as protective against atherosclerosis and cardiovascular disease.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Monoclonal

Cancer