Comparison

Human Keratin 8/KRT8 antibody

Item no. NKM-ATGA0253-50ul
Manufacturer NKMAX
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, FC, ICC, ELISA
Clone AT3D11
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG3 Kappa
Conjugate/Tag Unconjugated
Citations Moriya, T ., et al. (2006) Med Mol Morphol 39(1): 8-13
Leitner, A., et al. (2012) Biophys J 103(2): 195-201
NCBI NP_002264
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias KO,Keratin type II cytoskeletal 8,Keratin 8,K8,K2C8,CYK8,CK8,CARD2
Similar products Keratin, CARD2, CK-8, K8, CYK8, CK8, K2C8, KO, Cytokeratin 8, Keratin 8, CK 8, Cytokeratin8, Keratin8, Keratin type II cytoskeletal 8, Type II cytoskeletal 8, K-8, K2C-8, K2C 8, K 8, CYK 8, CARD-2, CARD 2, ATGA0253-10ug, ATGA0253-20ug, ATGA0253-50ug, ATGA0253-100ug, ATGA0253-250ug, ATGA0253-500ug, ATGA0253-1mg, ATGA0253-010, ATGA0253-020, ATGA0253-050, ATGA0253-100, ATGA0253-250, ATGA0253-500, ATGA0253-01M
Available
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF, FACS
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human KRT8 (1-483aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Cytoskeleton
Manufacturer - Search Terms
Type II cytoskeletal 8, KO, Keratin8, Keratin type II cytoskeletal 8, Keratin 8, Keratin, K-8, K8, K2C-8, K2C8, K2C 8, K 8, Cytokeratin8, Cytokeratin 8, CYK8, CYK 8, CK-8, CK8, CK 8, CARD-2, CARD2, CARD 2, ATGA0253-10ug, ATGA0253-20ug, ATGA0253-50ug, ATGA0253-100ug, ATGA0253-250ug, ATGA0253-500ug, ATGA0253-1mg, ATGA0253-010, ATGA0253-020, ATGA0253-050, ATGA0253-100, ATGA0253-250, ATGA0253-500, ATGA0253-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
available

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