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Human Beclin 1/BECN1 antibody

Human Beclin 1/BECN1 antibody

Item no.	NKM-ATGA0355-50ul
Manufacturer	NKMAX
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Antibodies Cell Biology Cell Status Autophagy Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, ICC, ELISA
Clone	AT45E8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Conjugate/Tag	Unconjugated
Citations	Liang XH., et al. (1998) J Virol. 72(11): 8586-8596. Takacs-Vellai K., et al. (2005) Curr Biol. 15(16): 1513-1517.
NCBI	NP_003757
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Beclin 1,Coiled-coil myosin-like BCL2-interacting protein,Protein GT197,Beclin 1 autophagy related,ATG6,ATG6 autophagy related 6 homolog,VPS30
Similar products	BECN1, Beclin1, ATGA0355-10ug, ATGA0355-20ug, ATGA0355-50ug, ATGA0355-100ug, ATGA0355-250ug, ATGA0355-500ug, ATGA0355-1mg, ATGA0355-10, ATGA0355-20, ATGA0355-50, ATGA0355-100, ATGA0355-250, ATGA0355-500, ATGA0355-1
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	ELISA, WB, ICC/IF, FACS
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	Beclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 is a mammalian ortholog of the yeast autophagy-related gene (Atg) 6 and BEC-1 in the C. elegans nematode. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human BECN (1-450aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-A affinity chromatography
Gene Category	Epigenomics (Transcription & Translation)
Manufacturer - Search Terms	Beclin1, BECN1, ATGA0355-10ug, ATGA0355-20ug, ATGA0355-50ug, ATGA0355-100ug, ATGA0355-250ug, ATGA0355-500ug, ATGA0355-1mg, ATGA0355-10, ATGA0355-20, ATGA0355-50, ATGA0355-100, ATGA0355-250, ATGA0355-500, ATGA0355-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 7/31/2025

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