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Human Otubain-1/OTUB1 antibody

Human Otubain-1/OTUB1 antibody

Item no.	NKM-ATGA0380-100ul
Manufacturer	NKMAX
Amount	100 ul
Quantity options	100 ul 50 ul
Category	Neuroscience Targets for Rodent Neurosciences Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC, ELISA
Clone	AT17E10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
Citations	Balakirev MY., et al. (2003) EMBO Rep. 4(5): 5175-5122. Soares L., et al. (2004) Nat Immunol. 5(1): 45-54.
NCBI	NP_060140
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ubiquitin thioesterase Otubain 1,OTB1,OTu1,ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1,OTu domain containing ubiquitin aldehyde binding protein 1,Otubain 1,ubiquitin specific processing protease OTuB1,ubiquitin thioesterase OTuB1.
Similar products	OTUB1, OTB1, Otubain 1, Otubain1, ubiquitin thioesterase Otubain 1, OTu1, ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1, OTu domain containing ubiquitin aldehyde binding protein 1, ubiquitin specific processing protease OTuB1, ubiquitin thioesterase OTuB1., ATGA0380-10ug, ATGA0380-20ug, ATGA0380-50ug, ATGA0380-100ug, ATGA0380-250ug, ATGA0380-500ug, ATGA0380-1mg, ATGA0380-10, ATGA0380-20, ATGA0380-50, ATGA0380-100, ATGA0380-250, ATGA0380-500, ATGA0380-1
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	ELISA, WB, ICC/IF
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	Otubain 1, also known as OTUB1, is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with an ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human OTUB1 (1-271aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-A affinity chromatography
Gene Category	Enzymes & Proteases
Manufacturer - Search Terms	Otubain1, OTUB1, ubiquitin thioesterase Otubain 1, OTB1, OTu1, ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1, OTu domain containing ubiquitin aldehyde binding protein 1, Otubain 1, ubiquitin specific processing protease OTuB1, ubiquitin thioesterase OTuB1., ATGA0380-10ug, ATGA0380-20ug, ATGA0380-50ug, ATGA0380-100ug, ATGA0380-250ug, ATGA0380-500ug, ATGA0380-1mg, ATGA0380-10, ATGA0380-20, ATGA0380-50, ATGA0380-100, ATGA0380-250, ATGA0380-500, ATGA0380-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 7/31/2025

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