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Human Frataxin antibody

Human Frataxin antibody

Item no.	NKM-ATGA0440-100ul
Manufacturer	NKMAX
Amount	100 ul
Quantity options	100 ul 50 ul
Category	Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC, ELISA
Clone	AT10E11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	Unconjugated
Citations	Campuzano V., et al. (1996) Science. 271(5254): 1423-7. Shan Y., et al. (2007) Hum Mol Genet. 16(8): 929-41.
NCBI	NP_000135
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CyaY,FA,FARR,FRDA,X25,FXN,Friedreich ataxia protein.
Available
Manufacturer - Type	Antibodies
Manufacturer - Applications	ELISA, WB, ICC/IF
Manufacturer - Category	Monoclonal Antibody
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human Frataxin (42-210aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot analysis, and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-A affinity chromatography
Gene Category	Signal Transduction
Manufacturer - Search Terms	Frataxin, CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein., ATGA0440-10ug, ATGA0440-20ug, ATGA0440-50ug, ATGA0440-100ug, ATGA0440-250ug, ATGA0440-500ug, ATGA0440-1mg, ATGA0440-10, ATGA0440-20, ATGA0440-50, ATGA0440-100, ATGA0440-250, ATGA0440-500, ATGA0440-1
Manufacturer - Similar Names	Frataxin, CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein., ATGA0440-10ug, ATGA0440-20ug, ATGA0440-50ug, ATGA0440-100ug, ATGA0440-250ug, ATGA0440-500ug, ATGA0440-1mg, ATGA0440-10, ATGA0440-20, ATGA0440-50, ATGA0440-100, ATGA0440-250, ATGA0440-500, ATGA0440-1
IF Comment	ICC/IF analysis of Frataxin in A549 cell line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human Frataxin antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
WB Comment	The cell lysates (10ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Frataxin antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : 293T cell lysate Lane 2. : Frataxin transfected 293T cell lysate

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/4/2025

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