Comparison

Human PGC1 alpha antibody

Item no. NKM-ATGA0466-100ul
Manufacturer NKMAX
Amount 100 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, FC, ICC, ELISA
Clone AT25C8
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Conjugate/Tag Unconjugated
Citations Lui Z., et al. (2016) Sci Rep. 6: 21382.
Li R., et al. (2016) Med Sci Monit. 22: 3229-3237.
NCBI NP_037393
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,PGC-1-alpha,PPAR-gamma coactivator 1-alpha,PPARGC-1-alpha,Ligand effect modulator 6,PPARGC1A,LEM6,PGC1,PGC1A,PPARGC1
Similar products PGC1 a, ATGA0466-10ug, ATGA0466-20ug, ATGA0466-50ug, ATGA0466-100ug, ATGA0466-250ug, ATGA0466-500ug, ATGA0466-1mg, ATGA0466-10, ATGA0466-20, ATGA0466-50, ATGA0466-100, ATGA0466-250, ATGA0466-500, ATGA0466-1
Available
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF, FACS
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. This protein can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Also, induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner and involved in the integration of the circadian rhythms and energy metabolism. They required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human PPARGC1A (300-540aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Epigenomics (Transcription & Translation)
Manufacturer - Search Terms
PGC1 a, ATGA0466-10ug, ATGA0466-20ug, ATGA0466-50ug, ATGA0466-100ug, ATGA0466-250ug, ATGA0466-500ug, ATGA0466-1mg, ATGA0466-10, ATGA0466-20, ATGA0466-50, ATGA0466-100, ATGA0466-250, ATGA0466-500, ATGA0466-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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