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Human EpCAM/TROP-1 antibody

Human EpCAM/TROP-1 antibody

Item no.	NKM-ATGA0515-100ul
Manufacturer	NKMAX
Amount	100 ul
Quantity options	100 ul 50 ul
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC, ELISA
Clone	AT36F10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Conjugate/Tag	Unconjugated
Citations	Litvinov. Sergey., et al. (1994) The Journal of Cell Biology 125(2): 437-46. Maetzel D., et al. (2009) Nat Cell Biol. 11(2): 162-71. Osta WA., et al. (2004) Cancer Res. 64(16): 5818-24. Munz M., et al. (2004) Oncogene 23(34): 5748-58. Armstrong A., et al. (2003) Cancer Biol Ther, 2(4): 320-6.
NCBI	NP_002345
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Epithelial cell adhesion molecules,CD326,KS1/4,KSA,M4S1,MIC18,MK-1,TACSTD1,TROP1,DIAR5,EGP,GA733 2,HNPCC8
Similar products	TROP1, EpCAM, ATGA0515-10ug, ATGA0515-20ug, ATGA0515-50ug, ATGA0515-100ug, ATGA0515-250ug, ATGA0515-500ug, ATGA0515-1mg, ATGA0515-10, ATGA0515-20, ATGA0515-50, ATGA0515-100, ATGA0515-250, ATGA0515-500, ATGA0515-1
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	ELISA, WB, ICC/IF
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description	Epithelial cell adhesion molecule (EPCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EPCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EPCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EPCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EPCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen	Recombinant human EpCAM/TROP-1 (24-265aa) purified from E. coli
Ab Usage	The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species	Human
Clonality	Monoclonal
Ab Purification Comment	By protein-A affinity chromatography
Gene Category	Tags & Cell Markers
Manufacturer - Search Terms	EpCAM, TROP1, ATGA0515-10ug, ATGA0515-20ug, ATGA0515-50ug, ATGA0515-100ug, ATGA0515-250ug, ATGA0515-500ug, ATGA0515-1mg, ATGA0515-10, ATGA0515-20, ATGA0515-50, ATGA0515-100, ATGA0515-250, ATGA0515-500, ATGA0515-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/2/2025

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