Comparison

Human BAK antibody

Item no. NKM-ATGA0523-50ul
Manufacturer NKMAX
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, FC, ICC, ELISA
Clone AT38E2
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Conjugate/Tag Unconjugated
Citations Birgit Kemmerling, et al. (2008) Plant Signal Behav, 3(2): 116-118.
Libo Shan, et al. (2008) Cell Host Microbe, 4(1): 17-27.
Xu-Bao Shi, et al. (2007) Proc Natl Acad Sci U S A, 104(50): 19983-19988.
Singh A, et al. Podophyllotoxin and Rutin Modulates Ionizing Radiation-Induced Oxidative Stress and Apoptotic Cell Death in Mice Bone Marrow and Spleen. (Front Immunol. 2017){https://pubmed.ncbi.nlm.nih.gov/28289414/}
Mebratu YA, et al. Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria. (Nat Commun. 2017){https://pubmed.ncbi.nlm.nih.gov/28986568/}
Liu P, et al. Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1. (Iran J Basic Med Sci. 2017){https://pubmed.ncbi.nlm.nih.gov/29299204/}
Loo LSW, et al. BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells. (Cell Death Dis. 2020){https://pubmed.ncbi.nlm.nih.gov/32424151/}
Shen J, et al. TLR9 regulates NLRP3 inflammasome activation via the NF-kB signaling pathway in diabetic nephropathy. (Diabetol Metab Syndr. 2022){https://pubmed.ncbi.nlm.nih.gov/35120573/}
NCBI NP_001179
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias BCL2-antagonist/killer 1, Apoptosis regulator BAK, BAK, BAK-LIKE, Bcl-2 homologous antagonist/killer, Bcl2-L-7, BAK-1, BAK 1, BAK like, Bak NT, BAK1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl2 homologous antagonist killer, Bcl2 like 7 Protein, BCL2-antagonist/killer 1, BCL2L7, CDN 1, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK
Similar products BAK, ATGA0523-10ug, ATGA0523-20ug, ATGA0523-50ug, ATGA0523-100ug, ATGA0523-250ug, ATGA0523-500ug, ATGA0523-1mg, ATGA0523-10, ATGA0523-20, ATGA0523-50, ATGA0523-100, ATGA0523-250, ATGA0523-500, ATGA0523-1
Available
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF, FACS
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
BAK1 encodes an receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtamembrane domain, and a kinase domain. BAK1 expression is associated with the progression of Prostate cancer (CaP). BAK1 appears to function in distinct receptor-signaling complexes to integrate multiple microbe-associated molecular pattern (MAMP) perception into downstream-signaling events. BAK1 can serve multiple purposes to simultaneously modulate MAMP-receptor complexes, BR signaling, and cell death for the benefit of bacterial infection, life style, and fitness.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human BAK (29-187aa) purified from E.coli
Ab Usage
The antibody has been tested by ELISA, Western blot, ICC/IF and FACS to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Gene Category
Apoptosis
Additional Comment Only
This product was produced from tissue culture supernatant.
Manufacturer - Search Terms
BAK, ATGA0523-10ug, ATGA0523-20ug, ATGA0523-50ug, ATGA0523-100ug, ATGA0523-250ug, ATGA0523-500ug, ATGA0523-1mg, ATGA0523-10, ATGA0523-20, ATGA0523-50, ATGA0523-100, ATGA0523-250, ATGA0523-500, ATGA0523-1
Manufacturer - Alternative Names
BCL2-antagonist/killer 1, Apoptosis regulator BAK, BAK, BAK-LIKE, Bcl-2 homologous antagonist/killer, Bcl2-L-7, BAK-1, BAK 1, BAK like, Bak NT, BAK1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl2 homologous antagonist killer, Bcl2 like 7 Protein, BCL2-antagonist/killer 1, BCL2L7, CDN 1, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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