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ELAVL1 Antibody

ELAVL1 Antibody

Item no.	OAAB19883
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Western Blot Immunofluorescence Senescence Primary Antibodies Astrocytoma By Organ Lung Cancer Breast Cancer Neuronal Cell Markers
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	Ma W.-J.,et al.J. Biol. Chem. 271:8144-8151(1996). Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Gallouzi I.-E.,et al.Science 294:1895-1901(2001). Li H.,et al.J. Biol. Chem. 277:44623-44630(2002).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HUR,Hua,MelG,ELAV1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	36 kDa
Manufacturer - Application Additional Information	WB: 1:1000
Gene symbol	ELAVL1
Product format	0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'- UUUU[AG]UUU-3' motif in vitro. With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA.
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OAAB19883-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 12/11/2025

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