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PLCG1 Antibody (Phospho-Tyr1253)

PLCG1 Antibody (Phospho-Tyr1253)

Item no.	OAAF07426
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Primary Antibodies Astrocytoma Immunostaining Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Polyclonal
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Sequence	SPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADH
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	1-phosphatidyl-D-myo-inositol-4,5-bisphosphate;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;inositoltrisphosphohydrolase;monophosphatidylinositol phosphodiesterase;NCKAP3;phosphatidylinositol phospholipase C;phosphoinositidase C;phosphoinositide phospholipase C;phosphoinositide phospholipase C-gamma-1;phospholipase C,gamma 1 (formerly subtype 148);phospholipase C-148;Phospholipase C-gamma-1;phospholipase C-II;PLC1;PLC148;PLC-148;PLCgamma1;PLC-gamma-1;PLC-II;triphosphoinositide phosphodiesterase.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	148 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:1000 ELISA: 1:20000
Gene symbol	PLCG1
Gene Fullname	phospholipase C gamma 1
Reconstitution and storage	-20°C
Description of target	Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Protein name	1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1
Clonality	Polyclonal
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Immunogen	The antiserum was produced against synthesized peptide derived from human PLCG1 around the phosphorylation site of Tyr1253.
Manufacturer - Specificity	PLCG1 (Phospho-Tyr1253) Antibody detects endogenous levels of PLCG1 only when phosphorylated at Tyr1253.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/27/2025

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