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TNFRSF11B Antibody (OAAJ07298)

TNFRSF11B Antibody (OAAJ07298)

Item no.	OAAJ07298
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Metabolism Glucose Homeostasis Antibodies Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot Primary Antibodies By Organ Lymphatic System Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Shipping Temperature	Wet Ice
Gene symbol	TNFRSF11B
Product format	Liquid
Reconstitution and storage	Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Description of target	Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Protein name	Tumor necrosis factor receptor superfamily member 11B
Clonality	Polyclonal
Purification	Immunogen affinity chromatography
Immunogen	Recombinant protein of human TNFRSF11B

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OAAJ07298-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 2/12/2026

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