ATF3 Antibody

Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies

ATF3

Liquid

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. [provided by RefSeq

https://www.ncbi.nlm.nih.gov/protein/AAH06322

Monoclonal

In 1x PBS, pH 7.4