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BNIP3L Antibody (OAAN03559)

BNIP3L Antibody (OAAN03559)

Item no.	OAAN03559
Manufacturer	AVIVA Systems Biology
Amount	50UL
Category	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Gene symbol	BNIP3L
Protein name	Tumor necrosis factor receptor superfamily member 10A
Molecular weight	24 kDa
Product format	Liquid
Gene id	665
Reconstitution and storage	Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.
Description of target	Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Purification	Affinity purification
Clonality	Polyclonal
Formulation	PBS with 0.02% sodium azide, 50% glyceron, pH 7.3
Immunogen	Recombinant Protein
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50UL

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Delivery expected until 9/11/2025

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