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LTA Antibody - N-terminal region

LTA Antibody - N-terminal region

Item no.	OABB00976
Manufacturer	AVIVA Systems Biology
Amount	100 ug/vial
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Neuronal Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cGMP-dependent 3',5'-cyclic phosphodiesterase;cGMP-stimulated phosphodiesterase 1;cGMP-stimulated phosphodiesterase 2;cGMP-stimulated phosphodiesterase 4;cGSPDE;CGS-PDE;cyclic GMP-stimulated phosphodiesterase;IDDPADS;PDE2A1;PED2A4;phosphodiesterase 2A,cGMP-stimulated.
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	PDE2A
Gene Fullname	phosphodiesterase 2A
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine.It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.
Protein name	cGMP-dependent 3', 5'-cyclic phosphodiesterase
Clonality	Recombinant Monoclonal
Purification	Affinity Purified
Immunogen	A synthesized peptide derived from human PDE2A
Dilution	Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line) (PubMed:24705027).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OABB00976-datasheet.pdf

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Amount: 100 ug/vial

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Delivery expected until 12/25/2025

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