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Mucin 1 Antibody - C-terminal region

Mucin 1 Antibody - C-terminal region

Item no.	OABB01466
Manufacturer	AVIVA Systems Biology
Amount	100 ug/vial
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Sarcoma Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies By Organ Breast Cancer Testicular & Prostate Cancer Immunostaining Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACE1;angiotensin I converting enzyme (peptidyl-dipeptidase A) 1;angiotensin-converting enzyme;carboxycathepsin;CD143;CD143 antigen;DCP;DCP1;dipeptidyl carboxypeptidase 1;dipeptidyl carboxypeptidase I;kininase II;peptidase P.
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	ACE
Gene Fullname	angiotensin I converting enzyme
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Mucin 1, cell surface associated(MUC1) or polymorphic epithelial mucin(PEM) is a mucin encoded by the MUC1 gene in humans. This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. It is mapped to 1q22. Mucin 1 is a transmembrane mucin normally expressed on the apical borders of secretory epithelial cells. Overexpression of Mucin 1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Mucin 1 stimulated ESR1-mediated transcription and contributed to estradiol-mediated growth and survival of breast cancer cells. This gene also can suppress pulmonary innate immunity, and its antiinflammatory activity may play an important modulatory role during microbial infection.
Protein name	Angiotensin-converting enzyme
Clonality	Recombinant Monoclonal
Purification	Affinity Purified
Immunogen	A synthesized peptide derived from human ACE1
Dilution	Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OABB01466-datasheet.pdf

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Amount: 100 ug/vial

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Delivery expected until 12/25/2025

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