EPH RECEPTOR A5 Antibody - C-terminal region (OABB02066)

EPH RECEPTOR A5

2044

EPH receptor A5 (ephrin type-A receptor 5) is a protein that in humans is encoded by the EPHA5 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described.

Immunogen affinity purified.

A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor A5 (1001-1032aa TLEDLRRLGVTLVGHQKKIMNSLQEMKVQ LVN), different from the related mouse sequence by two amino acids.