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AKT1 Antibody (OABF00057-100UL)

AKT1 Antibody (OABF00057-100UL)

Item no.	OABF00057
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Obesity Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Primary Antibodies By Organ Lung Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	FC, IF, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cell surface retention sequence binding protein-1;Cell surface retention sequence-binding protein 1;CRSBP-1;extracellular link domain-containing 1;extracellular link domain-containing protein 1;HAR;hyaluronic acid receptor;lymphatic vessel endothelial hyaluronic acid receptor 1;LYVE-1;XLKD1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	LYVE1
Gene Fullname	lymphatic vessel endothelial hyaluronan receptor 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
Protein name	Lymphatic vessel endothelial hyaluronic acid receptor 1
Clonality	Recombinant Monoclonal
Purification	Affinity Purified
Immunogen	A synthesized peptide derived from Human LYVE1
Dilution	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/25/2025

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