HDAC1 Antibody (OACA02422)

histone deacetylase 1

55 kDa

3065

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Caprylic Acid Ammonium Sulfate Precipitation purified

Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300

Wet Ice