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BMPR1A Antibody

BMPR1A Antibody

Item no.	OACA02652
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14:2121-2127(2004). [2]"Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties."Mahlawat P., Ilangovan U., Biswas T., Sun L.Z., Hinck A.P.Biochemistry 51:6328-6341(2012). [3]"Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis."Howe J.R., Bair J.L., Sayed M.G., Anderson M.E., Mitros F.A., Petersen G.M., Velculescu V.E., Traverso G., Vogelstein B.Nat. Genet. 28:184-187(2001).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	10q23del;activin A receptor,type II-like kinase 3;activin receptor-like kinase 3;ACVRLK3;ALK3;ALK-3;BMP type-1A receptor;BMPR-1A;bone morphogenetic protein receptor type-1A;bone morphogenetic protein receptor,type IA;CD292;serine/threonine-protein kinase receptor R5;SKR5.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	BMPR1A
Gene Fullname	bone morphogenetic protein receptor type 1A
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Nucleotide accession_num	NM_004329
Protein accession_num	NP_004320
Protein name	Bone morphogenetic protein receptor type-1A
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Bone morphogenetic protein receptor type-1A protein (177-532AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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