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BLOC1S1 Antibody

BLOC1S1 Antibody

Item no.	OACA02723
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining small GTPases Arf Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1] "Molecular cloning of a novel human cDNA, RT14, containing a putative ORF highly conserved between human, fruit fly, and nematode."Watanabe T.K., Fujiwara T., Shinomiya H., Kuga Y., Hishigaki H., Nakamura Y., Hirai Y.DNA Res. 2:235-237(1995) [2] "T
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	biogenesis of lysosome-related organelles complex 1 subunit 1;BLOC-1 subunit 1;BLOS1;BORCS1;GCN5 (general control of amino-acid synthesis,yeast,homolog)-like 1;GCN5 general control of amino-acid synthesis 5-like 1;GCN5L1;GCN5-like protein 1;MICoA;MTA1-interacting coactivator;Protein RT14;RT14.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	BLOC1S1
Gene Fullname	biogenesis of lysosomal organelles complex 1 subunit 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (PubMed:17182842). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).
Nucleotide accession_num	NM_001487
Protein accession_num	NP_001478
Protein name	Biogenesis of lysosome-related organelles complex 1 subunit 1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 1 protein (1-153AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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