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GRIA3 Antibody

GRIA3 Antibody

Item no.	OACA03067
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Molecular Targets for Neuroscience Neural Adhesion Molecules Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Mutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans." Wu Y., Arai A.C., Rumbaugh G., Srivastava A.K., Turner G., Hayashi T., Suzuki E., Jiang Y., Zhang L., Rodriguez J., Boyle J., Tarpey P., Raymond F.L., Nevelsteen J., Froyen G., Stratton M., Futreal A., Gecz J. Wang T. Proc. Natl. Acad. Sci. U.S.A. 104:18163-18168(2006). [2]"Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins." Kato A.S., Gill M.B., Ho M.T., Yu H., Tu Y., Siuda E.R., Wang H., Qian Y.W., Nisenbaum E.S., Tomita S., Bredt D.S. Neuron 68:1082-1096(2009). [3]"Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq." Amir R., Dahle E.J., Toriolo D., Zoghbi H.Y. Am. J. Med. Genet. 90:69-71(1999).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AMPA-selective glutamate receptor 3;dJ1171F9.1;GluA3;gluR-3;GLUR3;GLURC;GLUR-C;GLUR-K3;glutamate receptor 3;glutamate receptor C;Glutamate receptor ionotropic,AMPA 3;glutamate receptor subunit 3;glutamate receptor,ionotrophic,AMPA 3;glutamate receptor,ionotropic,AMPA 3;MRX94;MRXSW.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GRIA3
Gene Fullname	glutamate ionotropic receptor AMPA type subunit 3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Nucleotide accession_num	NM_000828
Protein accession_num	NP_000819
Protein name	Glutamate receptor 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Glutamate receptor 3 protein (151-250AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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