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ID2 Antibody

ID2 Antibody

Item no.	OACA03126
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD."Kim J.Y., Chu K., Kim H.J., Seong H.A., Park K.C., Sanyal S., Takeda J., Ha H., Shong M., Tsai M.J., Cho
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	bHLHb26;cell growth-inhibiting gene 8;class B basic helix-loop-helix protein 26;DNA-binding protein inhibitor ID2;DNA-binding protein inhibitor ID-2;GIG8;helix-loop-helix protein ID2;ID2A;ID2H;inhibitor of differentiation 2;Inhibitor of DNA binding 2;inhibitor of DNA binding 2,dominant negative helix-loop-helix protein;inhibitor of DNA binding 2,HLH protein.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ID2
Gene Fullname	inhibitor of DNA binding 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
Nucleotide accession_num	NM_002166
Protein accession_num	NP_002157
Protein name	DNA-binding protein inhibitor ID-2
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human DNA-binding protein inhibitor ID-2 protein (1-134AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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