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ITGA2B Antibody

ITGA2B Antibody

Item no.	OACA03168
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Neural Adhesion Molecules Antibodies Flow Cytometry Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S. Nat. Genet. 36:40-45(2004). [2]"Organization of the gene for platelet glycoprotein IIb." Heidenreich R., Eisman R., Surrey S., Delgrosso K., Bennett J.S., Schwartz E., Poncz M. Biochemistry 29:1232-1244(1990). [3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	alphaIIb protein;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPalpha IIb;GPIIb;GT;GT1;GTA;HPA3;integrin alpha-IIb;integrin,alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex,antigen CD41);platelet fibrinogen receptor,alpha subunit;platelet glycoprotein IIb of IIb/IIIa complex;platelet membrane glycoprotein IIb;platelet-specific antigen BAK;PPP1R93;protein phosphatase 1,regulatory subunit 93.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ITGA2B
Gene Fullname	integrin subunit alpha 2b
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Nucleotide accession_num	NM_000419
Protein accession_num	NP_000410
Protein name	Integrin alpha-IIb
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Integrin alpha-IIb protein (639-887AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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