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MMP13 Antibody

MMP13 Antibody

Item no.	OACA04136
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Regulation of Appetite Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Cell Status Necrosis Mesothelioma Immunohistochemistry Western Blot ELISA Immunofluorescence Cell Stainings ECM Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Colorectal Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Mutations in MMP9 and MMP13 determine the mode of inheritance and the clinical spectrum of metaphyseal anadysplasia."Lausch E., Keppler R., Hilbert K., Cormier-Daire V., Nikkel S., Nishimura G., Unger S., Spranger J., Superti-Furga A., Zabel B.Am. J.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CLG3;collagenase 3;MANDP1;matrix metalloproteinase 13 (collagenase 3);Matrix metalloproteinase-13;MDST;MMP-13.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MMP13
Gene Fullname	matrix metallopeptidase 13
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
Nucleotide accession_num	NM_002427
Protein accession_num	NP_002418
Protein name	Collagenase 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Collagenase 3 protein (104-471AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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