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IFNAR2 Antibody

IFNAR2 Antibody

Item no.	OACA04238
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Targets for Rodent Neurosciences Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Adenocarcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Structural linkage between ligand discrimination and receptor activation by type I interferons." Thomas C., Moraga I., Levin D., Krutzik P.O., Podoplelova Y., Trejo A., Lee C., Yarden G., Vleck S.E., Glenn J.S., Nolan G.P., Piehler J., Schreiber G., Garcia K.C. Cell 146:621-632(2011). [2]"Intermolecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric reverse-protonation and two-dimensional NOESY." Nudelman I., Akabayov S.R., Schnur E., Biron Z., Levy R., Xu Y., Yang D., Anglister J. Biochemistry 49:5117-5133(2010). [3]"Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex." Quadt-Akabayov S.R., Chill J.H., Levy R., Kessler N., Anglister J. Protein Sci. 15:2656-2668(2006).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	human interferon alpha/beta receptor;IFNABR;IFN-alpha/beta receptor 2;IFNalpha/beta receptor subunit 2;IFN-alpha-REC;IFNARB;IFN-R;IFN-R-2;IMD45;interferon (alpha,beta and omega) receptor 2;interferon alpha binding protein;interferon alpha/beta receptor 2;interferon receptor;interferon-alpha/beta receptor beta chain;type I interferon receptor 2.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	IFNAR2
Gene Fullname	interferon alpha and beta receptor subunit 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950).
Nucleotide accession_num	NM_000874
Protein accession_num	NP_000865
Protein name	Interferon alpha/beta receptor 2
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Interferon alpha/beta receptor 2 protein (27-243AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/11/2025

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