« Back
Home /
DGUOK Antibody

DGUOK Antibody

Item no.	OACA04777
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies CHiP Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Molecular insight into mitochondrial DNA depletion syndrome in two patients with novel mutations in the deoxyguanosine kinase and thymidine kinase 2 genes." Wang L., Limongelli A., Vila M.R., Carrara F., Zeviani M., Eriksson S. Mol. Genet. Metab. 84:75-82(2005) . [2]"Mitochondrial DNA depletion and dGK gene mutations." Salviati L., Sacconi S., Mancuso M., Otaegui D., Camano P., Marina A., Rabinowitz S., Shiffman R., Thompson K., Wilson C.M., Feigenbaum A., Naini A.B., Hirano M., Bonilla E., DiMauro S., Vu T.H. Ann. Neurol. 52:311-317(2002). [3]"Structural basis for substrate specificities of cellular deoxyribonucleoside kinases." Johansson K., Ramaswamy S., Ljungcrantz C., Knecht W., Piskur J., Munch-Petersen B., Eriksson S., Eklund H. Nat. Struct. Biol. 8:616-620(2001).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	deoxyadenosine kinase,mitochondrial;deoxyguanosine kinase,mitochondrial;dGK;MTDPS3;NCPH;NCPH1;PEOB4.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DGUOK
Gene Fullname	deoxyguanosine kinase
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.
Nucleotide accession_num	NM_001318859
Protein accession_num	NP_001305788
Protein name	Deoxyguanosine kinase, mitochondrial
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Deoxyguanosine kinase, mitochondrial protein (40-277AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OACA04777-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 50 ug

available

Delivery expected until 10/30/2025

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer