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DOK1 Antibody

DOK1 Antibody

Item no.	OACA05916
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding."Oxley C.L., Anthis N.J., Lowe E.D.,Vakonakis I., Campbell I.D., Wegener K.L.J. Biol. Chem. 83:5420-5426(2008). [2]"The
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	docking protein 1;Downstream of tyrosine kinase 1;p62(dok);P62DOK;pp62.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	DOK1
Gene Fullname	docking protein 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Nucleotide accession_num	NM_001197260
Protein accession_num	NP_001184189
Protein name	Docking protein 1
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Docking protein 1 protein (1-481AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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