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GRIA1 Antibody

GRIA1 Antibody

Item no.	OACA06638
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Colorectal Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors." Salussolia C.L., Gan Q., Kazi R., Singh P., Allopenna J., Furukawa H., Wollmuth L.P.J. Neurosci. 33:9840-9845(2013). [2]Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating." Shi Y., Suh Y.H., Milstein A.D., Isozaki K., Schmid S.M., Roche K.W., Nicoll R.A.Proc. Natl. Acad. Sci. U.S.A. 107:16315-16319(2010). [3]Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins."Kato A.S., Gill M.B., Ho M.T., Yu H., Tu Y., Siuda E.R., Wang H., Qian Y.W., Nisenbaum E.S., Tomita S., Bredt D.S.Neuron 68:1082-1096(2010).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AMPA 1;AMPA-selective glutamate receptor 1;GluA1;GLUH1;gluR-1;GLUR1;gluR-A;GLURA;gluR-K1;glutamate receptor 1;Glutamate receptor ionotropic,AMPA 1;glutamate receptor,ionotropic,AMPA 1;HBGR1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GRIA1
Gene Fullname	glutamate ionotropic receptor AMPA type subunit 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Nucleotide accession_num	NM_000827
Protein accession_num	NP_000818
Protein name	Glutamate receptor 1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Glutamate receptor 1 protein (19-300AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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