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MAD2L1 Antibody

MAD2L1 Antibody

Item no.	OACA06715
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining Neurodegeneration Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]Insights into Mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric Mad2 dimer."Yang M., Li B., Liu C.-J., Tomchick D.R., Machius M., Rizo J., Yu H., Luo X.PLoS Biol. 6:E50-E50(2008). [2]p31comet blocks Mad2 activation through structural mimicry."Yang M., Li B., Tomchick D.R., Machius M., Rizo J., Yu H., Luo X.Cell 131:744-755(2007). [3]The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint." Mapelli M., Massimiliano L., Santaguida S., Musacchio A. Cell 131:730-743(2007).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HSMAD2;MAD2;MAD2 (mitotic arrest deficient,yeast,homolog)-like 1;MAD2 mitotic arrest deficient-like 1;MAD2-like protein 1;mitotic arrest deficient 2-like protein 1;mitotic arrest deficient,yeast,homolog-like 1;mitotic spindle assembly checkpoint protein MAD2A.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MAD2L1
Gene Fullname	mitotic arrest deficient 2 like 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Nucleotide accession_num	NM_002358
Protein accession_num	NP_002349
Protein name	Mitotic spindle assembly checkpoint protein MAD2A
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Mitotic spindle assembly checkpoint protein MAD2A protein (1-205AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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