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CD74 Antibody

CD74 Antibody

Item no.	OACA06816
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Primary Antibodies By Organ Lung Cancer Colorectal Cancer Breast Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IP, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S." Guncar G., Pungercic G., Klemencic I., Turk V., Turk D. EMBO J. 18:793-803(1999). [2]Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii." Jasanoff A., Wagner G., Wiley D.C.EMBO J. 17:6812-6818(1998). [3]The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3."Ghosh P., Amaya M., Mellins E., Wiley D.C.Nature 378:457-462(1995).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD74 antigen (invariant polypeptide of major histocompatibility complex,class II antigen-associated);CD74 molecule,major histocompatibility complex,class II invariant chain;DHLAG;gamma chain of class II antigens;HLA class II histocompatibility antigen gamma chain;HLADG;HLA-DR antigens-associated invariant chain;HLA-DR-gamma;Ia antigen-associated invariant chain;Ia-associated invariant chain;Ia-GAMMA;II;MHC HLA-DR gamma chain;p33.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CD74
Gene Fullname	CD74 molecule
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Nucleotide accession_num	NM_001025158
Protein accession_num	NP_001020329
Protein name	HLA class II histocompatibility antigen gamma chain
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human HLA class II histocompatibility antigen gamma chain protein (137-296AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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