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CEACAM3 Antibody

CEACAM3 Antibody

Item no.	OACA07341
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry ELISA Primary Antibodies Immunostaining small GTPases Rho Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens." Schmitter T., Agerer F., Peterson L., Muenzner P., Hauck C.R. J. Exp. Med. 199:35-46(2003). [3]"Immunoreceptor tyrosine-based activation motif phosphorylation during engulfment of Neisseria gonorrhoeae by the neutrophil-restricted CEACAM3 (CD66d) receptor."McCaw S.E., Schneider J., Liao E.H., Zimmermann W., Gray-Owen S.D. Mol. Microbiol. 49:623-637(2002). [3]"The microbial receptor CEACAM3 is linked to the calprotectin complex in granulocytes."Streichert T., Ebrahimnejad A., Ganzer S., Flayeh R., Wagener C., Bruemmer J.Biochem. Biophys. Res. Commun. 289:191-197(2000).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	carcinoembryonic antigen CGM1;carcinoembryonic antigen gene family member 1;carcinoembryonic antigen related cell adhesion molecule 3;carcinoembryonic antigen-related cell adhesion molecule 3;CD66D;CD66d antigen;CEA;CGM1;nonspecific cross-reacting antigen;W264;W282.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CEACAM3
Gene Fullname	CEA cell adhesion molecule 3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
Nucleotide accession_num	NM_001277163
Protein accession_num	NP_001264092
Protein name	Carcinoembryonic antigen-related cell adhesion molecule 3
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 3 protein (1-135AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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